Alfredo Rus Sánchez

My PhD research centers on the computational design of PROTACs (Proteolysis-Targeting Chimeras), a novel class of therapeutics that selectively degrade target proteins.

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At the Institute of Medicinal Chemistry (IQM-CSIC) in Madrid, I model ternary complexes involved in ubiquitin-mediated protein degradation, combining molecular docking, bioinformatics, and AI-driven workflows to predict viable candidates in silico.

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This project is part of the CSIC Momentum program, promoting digital talent through AI-based science. Beyond drug discovery, my goal is to develop reproducible computational tools for medicinal chemistry.